生物醫學研究用的實驗動物一般是需要無特定病原（specific pathogen-free, SPF），而非人類靈長類動物（nonhuman primates, NHPs）定義為SPF的最低標準，是指無下列病原－結核菌 (Mycobacterium tuberculosis, M.tb.）、疱疹B病毒 (herpes B virus, cercopithecine herpesvirus 1, CHV-1)、猿猴免疫抑制病毒 (simian immunodeficiency virus, SIV)、猿猴D型反轉錄病毒 (simian type D retrovirus, SRV) 與猿猴白血病病毒 (simian T cell lymphotropic/leukemia virus, STLV)。

Specific pathogen-free (SPF) experimental animals are now commonly requested for research purposes. Common definition of SPF in nonhuman primates (NHPs) is free of Mycobacterium tuberculosis (M.tb.), simian immunodeficiency virus (SIV), simian type D retrovirus (SRV), herpes B virus/Cercopithecine herpesvirus 1 (CHV-1), and simian T cell lymphotropic/leukemia virus (STLV). SIV, SRV, and STLV are belonged to Simian Retroviruses.